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Development of the Canadian beef reference herd for gene mapping studies
S M Schmutz1, F C Buchanan, D C Winkelman-Sim
1Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon, Canada. schmutz@sask.usask.ca
Theriogenology
|April 9, 2001
Summary
Researchers mapped quantitative trait loci (QTL) in beef cattle using a full-sib design across six breeds. This large-scale embryo transfer study optimized gene mapping and carcass quality data collection.
Area of Science:
- Animal Genetics
- Quantitative Genetics
- Livestock Breeding
Background:
- Mapping quantitative trait loci (QTL) is crucial for improving beef cattle genetics.
- A large-scale, short-timeframe experiment was designed for efficient gene mapping.
- Utilizing a full-sib design allows for tracking genetic information from both parents.
Purpose of the Study:
- To initiate a project for mapping quantitative trait loci (QTL) in beef cattle.
- To develop a specialized herd for gene mapping using embryo transfer technology.
- To enable comprehensive genetic and carcass quality data collection from both parents.
Main Methods:
- A full-sib design was employed across six Bos taurus breeds.
- Large-scale embryo transfer was utilized to establish the experimental herd.
- Superovulation protocols were applied, with repeatability and correlation analyses conducted.
Main Results:
- Repeatability of superovulation response was significant across three flushes per female.
- Superovulation response showed a negative correlation with the donor's backfat.
- Crossbred embryos exhibited higher survival rates compared to purebred embryos.
Conclusions:
- The full-sib design facilitated efficient gene mapping and dual-parent carcass data acquisition.
- Embryo transfer proved effective for rapid herd development for genetic studies.
- Crossbred embryos demonstrate superior survival, offering potential advantages in breeding programs.