Related Experiment Videos
The effect of time of day and repeat reliability on the fast flicker multifocal ERG
B Heinemann-Vernaleken1, A Palmowski, R Allgayer
1Department of Ophthalmology and Eye Hospital, University of the Saarland, Homburg, Germany. aubhei@med-rz.uni-sb.de
Purpose:
To investigate the possible influence of different times of the day on multifocal ERG recordings in normals.
Methods:
10 healthy volunteers underwent multifocal ERG recordings (VERIS 3.1.1.) 3 times a day, at 10:30 am, 1:30 pm and 4:30 pm using a fast flicker stimulus of 103 hexagons. Additional night-time recordings were performed in 2 subjects. The first-order and dominant part of the second order response component were analyzed.
Results:
Neither peak latencies nor peak-to-peak amplitudes showed significant changes during the day (p >0.05). Comparison between night and day time recordings did also not reveal an influence of a circadian rhythm on the MF-ERG.
Conclusions:
No significant influence of the time of the day suggestive of a circadian rhythm could be observed. Light adaptation due to preadaptation and the flicker sequence used could be a possible cause for these results.