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[The effect of myocardial revascularization on global and regional systolic and diastolic left and right ventricular

B Bacior1, W M Szot, A Hubalewska-Hoła

  • 1I Klinika Kardiologii Collegium Medicum, Uniwersytetu Jagiellońsklego w Krakowie.

Przeglad Lekarski
|April 11, 2001
PubMed

Insights

Myocardial revascularization, including percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG), enhances left ventricular function. However, it shows no significant impact on overall right ventricular performance in patients with coronary artery disease.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Diagnostic Imaging

Background:

  • Coronary artery disease (CAD) significantly impacts cardiac function.
  • Myocardial revascularization aims to restore blood flow and improve ventricular performance.
  • Evaluating the effects of PTCA and CABG on both left and right ventricular function is crucial.

Purpose of the Study:

  • To assess the impact of percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass grafting (CABG) on right and left ventricular systolic and diastolic function.
  • To evaluate changes in segmental wall motion following myocardial revascularization procedures.
  • To compare the functional outcomes of PTCA versus CABG in patients with CAD.

Main Methods:

  • Radionuclide angiocardiography was performed at baseline and 3 months post-procedure in 27 CAD patients (17 CABG, 10 PTCA).
  • Key parameters assessed included ejection fraction (EF), 1/3EF, maximal emptying rate (MER), maximal filling rate (MFR), 1/3 filling fraction (1/3FF), and segmental wall motion (S1-S9).
  • Statistical analysis compared pre- and post-procedure functional parameters.

Main Results:

  • Left ventricular ejection fraction (LVEF) improved in 29.4% of CABG patients and 40% of PTCA patients.
  • Segmental wall motion improved in revascularized areas, with exceptions in left ventricular septal segments post-CABG.
  • Global right ventricular function remained largely unchanged, though septal segment EF increased post-CABG.

Conclusions:

  • Myocardial revascularization effectively improves left ventricular systolic and diastolic function.
  • Global right ventricular performance is generally unaffected by PTCA or CABG.
  • CABG altered septal segment ejection fraction, while successful PTCA of the LAD improved left ventricular septal segment EF.
Abstract

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