Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Resistant tuberculosis in Denmark].

V O Thomsen1, I S Johansen, J O Bauer

  • 1Statens Serum Institut, mykobakteriologisk laboratorium og epidemiologisk afdeling, København. vot@ssi.dk

Ugeskrift for Laeger
|April 11, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Treatment and outcomes in patients with non-TB mycobacterial pulmonary disease: a single-centre study.

IJTLD open·2026
Same author

Clinical standards for antimicrobial stewardship in TB care.

IJTLD open·2025
Same author

Borderline T-SPOT.TB results: test reliability, patient characteristics, and TB progression.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2025
Same author

Urgent request for pretomanid label expansion to align with WHO guidelines and improve treatment accessibility and efficacy.

IJTLD open·2025
Same author

Mortality and causes of death in non-tuberculous mycobacterial pulmonary disease.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2025
Same author

Associations between mental illness, TB risk and migrant status.

IJTLD open·2024
Same journal

[Mosaicism as a cause of Cowden syndrome].

Ugeskrift for laeger·2026
Same journal

[Thyrotoxic crisis with cardiogenic shock].

Ugeskrift for laeger·2026
Same journal

[Mindfulness-based cognitive therapy in the treatment of depression].

Ugeskrift for laeger·2026
Same journal

[Fitness].

Ugeskrift for laeger·2026
Same journal

[Risk of developing cataract related to fluoroscopy].

Ugeskrift for laeger·2026
Same journal

[Obturator hernia with small bowel ileus presenting as hip pain in an elderly woman].

Ugeskrift for laeger·2026
See all related articles

Multidrug-resistant tuberculosis (MDR TB) surveillance in Denmark revealed low overall drug resistance. However, active transmission of isoniazid- and streptomycin-resistant Mycobacterium tuberculosis strains was detected, necessitating ongoing monitoring.

Area of Science:

  • Microbiology
  • Epidemiology
  • Public Health

Context:

  • Rising rates of multidrug-resistant tuberculosis (MDR TB) globally pose a significant public health threat.
  • Denmark, situated near regions with high MDR TB incidence, required an assessment of its own drug resistance landscape.
  • Understanding drug resistance patterns is crucial for effective tuberculosis control strategies.

Purpose:

  • To evaluate the incidence and trends of drug resistance in Mycobacterium tuberculosis isolates in Denmark between 1991 and 1998.
  • To identify specific drug-resistant strains and their epidemiological characteristics within the Danish population.
  • To assess the risk of imported versus domestically acquired drug-resistant tuberculosis.

Summary:

  • Susceptibility testing was performed on isolates from 85.4% of notified tuberculosis patients from 1991-1998.

Related Experiment Videos

  • Overall drug resistance remained stable, with multidrug resistance (MDR) at 0.5%.
  • A notable finding was the identification of an isoniazid- and streptomycin-resistant RFLP-cluster among untreated Danes aged 25-54, indicating active transmission.

    • Impact:

    • The study identified active transmission of specific drug-resistant strains, highlighting the need for continued surveillance.
    • Findings suggest that while overall resistance is low, localized transmission clusters require targeted public health interventions.
    • This research provides valuable data for national tuberculosis programs to refine control and prevention efforts against drug-resistant tuberculosis.