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Capsular Serotyping of Streptococcus pneumoniae Using the Quellung Reaction
Published on: February 24, 2014
Use of antiserum-coated latex particles for serotyping Streptococcus pneumoniae
1Infectious Diseases Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan.
Microbiology and Immunology
|April 11, 2001
Abstract:
The Quellung reaction provides a standard means for serotyping Streptococcus pneumoniae, but it requires microscopic examination with skillful technique. We have developed an improved agglutination method with anti-rabbit IgG-coated latex particles, which are sensitized with pooled antisera for serotyping/serogrouping S. pneumoniae. Our method is as specific and sensitive as the Quellung test, and much easier to perform.

