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A study of infectious intestinal disease in England: risk factors associated with group A rotavirus in children

D Sethi1, P Cumberland, M J Hudson

  • 1London School of Hygiene and Tropical Medicine, England, UK.

Epidemiology and Infection
|April 11, 2001
PubMed

Insights

Living in rented council housing and contact with sick individuals are key risk factors for rotavirus infectious intestinal disease (IID) in children. Breastfeeding offers protection for infants against this common childhood illness.

Area of Science:

  • Pediatric infectious diseases
  • Epidemiology of viral gastroenteritis
  • Public health and environmental factors

Background:

  • Infectious intestinal disease (IID) caused by rotavirus group A is a significant cause of childhood illness.
  • Identifying specific risk factors is crucial for developing targeted prevention strategies.

Purpose of the Study:

  • To determine risk factors associated with rotavirus group A infectious intestinal disease (IID) in children under 16 years.
  • To investigate environmental, social, and feeding-related factors influencing rotavirus infection.

Main Methods:

  • A case-control study design was employed.
  • Cases of rotavirus IID were identified through general practitioners and community cohorts.
  • Matched controls were selected for comparison.

Main Results:

  • Living in rented council housing (adjusted OR = 3.78) and contact with individuals ill with IID (OR = 3.45) were significant risk factors.
  • Larger accommodations (more than five rooms, OR = 0.72) were associated with a reduced risk.
  • Bottle feeding (with or without breastfeeding) in infants increased risk (OR = 9.06).

Conclusions:

  • Sporadic rotavirus IID in children is linked to specific housing conditions and social contact.
  • Preventive measures should consider household crowding and transmission routes.
  • Breastfeeding demonstrates a protective effect in infants against rotavirus infection.
Abstract

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