Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Corynebacterium bovis as a pathogen in rabbits.

S N Arseculeratne, C Navaratnam

Research in Veterinary Science

|March 1, 1975

Summary

Corynebacterium bovis caused testicular and lung abscesses in a laboratory rabbit, which was reproducible in another rabbit. Antibody responses suggest cross-reactivity with Mycobacterium tuberculosis antigens.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A re-appraisal of the conventional history of antibiosis and Penicillin.

Mycoses·2017

Same author

The regional sero-epidemiology of rhinosporidiosis in Sri Lankan humans and animals.

Acta tropica·2011

Same author

Publishing in learned journals.

The Indian journal of medical research·2010

Same author

Patterns of rhinosporidiosis in Sri Lanka: comparison with international data.

The Southeast Asian journal of tropical medicine and public health·2010

Same author

The use of MTT [3-(4, 5-dimethyl-2-thiazolyl) -2, 5-diphenyl -2H- tetrazolium bromide]-reduction as an indicator of the effects of strain-specific, polyclonal rabbit antisera on Candida albicans and C. krusei.

Indian journal of medical microbiology·2007

Same author

Recent advances in rhinosporidiosis and Rhinosporidium seeberi.

Indian journal of medical microbiology·2007

Area of Science:

Veterinary Microbiology
Infectious Diseases

Background:

Corynebacterium bovis is a bacterium found in various animal species.
Its pathogenicity, particularly in dairy animals, is not well-established.
Laboratory animals can serve as models for studying bacterial infections.

Purpose of the Study:

To investigate the pathogenicity of a Corynebacterium bovis isolate from a rabbit.
To determine the immune response elicited by the isolated bacterium.
To assess the potential cross-reactivity with Mycobacterium tuberculosis antigens.

Main Methods:

Isolation and identification of Corynebacterium bovis from a rabbit abscess and lung.
Experimental infection of a healthy rabbit via intravenous injection.
Serological testing using agglutination assays with the isolated Corynebacterium and sensitized kaolin particles.

Main Results:

Corynebacterium bovis was isolated from a chronic testicular abscess and lung of a rabbit.
Experimental intravenous injection of the isolate caused disease in the inguinal and vulval regions of another rabbit.
Sera from infected rabbits showed rising antibody titers against the isolate and Mycobacterium tuberculosis phosphatide antigen.

Conclusions:

Corynebacterium bovis demonstrated pathogenicity in a laboratory rabbit model.
The observed antibody response suggests potential cross-reactivity between C. bovis and Mycobacterium tuberculosis antigens.
Re-evaluation of Corynebacterium bovis pathogenicity in dairy animals is warranted due to literature uncertainties.

Related Experiment Videos