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Urinary tract infection in neurogenic bladder.
T Matsumoto1, K Takahashi, N Manabe
1Department of Urology, University of Occupational and Environmental Health Japan, Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka 807, Japan.
International Journal of Antimicrobial Agents
|April 11, 2001
Summary
Urinary tract infections (UTIs) are common in neurogenic bladder. Prompt antimicrobial chemotherapy, potentially with newer antibiotics, can shorten febrile periods associated with these infections.
Area of Science:
- Urology
- Infectious Diseases
- Nephrology
Background:
- Neurogenic bladder dysfunction frequently leads to urinary tract infections (UTIs).
- UTIs are the most common complication, progressing to febrile diseases in chronic cases, often with a hypertonic bladder.
- Identifying pre-febrile symptoms aids in timely intervention.
Purpose of the Study:
- To review the management and outcomes of urinary tract infections in patients with neurogenic bladder.
- To evaluate the effectiveness of antimicrobial chemotherapy in reducing febrile periods.
Main Methods:
- Retrospective analysis of 229 patients with neurogenic bladder treated between January 1993 and December 1998.
- Focus on patients experiencing urinary tract infections and febrile episodes.
- Evaluation of antimicrobial treatment strategies, including newer generation antibiotics.
Main Results:
- Urinary tract infections are a significant complication in neurogenic bladder patients.
- Early initiation of antimicrobial chemotherapy is crucial.
- Newer cephalosporins and carbapenems demonstrated potential in shortening febrile illness duration.
Conclusions:
- Prompt diagnosis and treatment of UTIs are essential for managing neurogenic bladder complications.
- Antimicrobial chemotherapy, particularly with advanced agents, can effectively reduce febrile episodes.
- Further research into optimal antibiotic strategies for neurogenic bladder UTIs is warranted.