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Inflammatory linear verrucous epidermal nevus and arthritis: a new association

S Al-Enezi1, A M Huber, B R Krafchik

  • 1Division of Rheumatology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Insights

Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare childhood skin condition. This study describes a new association between ILVEN and arthritis in two children, suggesting management strategies.

Area of Science:

  • Dermatology
  • Pediatrics
  • Rheumatology

Background:

  • Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare, congenital skin disorder characterized by its linear, verrucous, and inflammatory nature.
  • ILVEN typically presents in early childhood and can cause significant cosmetic and psychological distress.

Observation:

  • This report details two pediatric cases presenting with concurrent ILVEN and arthritis.
  • The co-occurrence of these conditions was previously undocumented in medical literature.

Findings:

  • The study highlights a novel association between ILVEN and arthritis in pediatric patients.
  • Clinical and diagnostic observations suggest a potential link warranting further investigation.

Implications:

  • This finding expands the understanding of ILVEN's potential systemic manifestations.
  • Early recognition and appropriate management of arthritis in children with ILVEN are crucial for improving patient outcomes.

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