Related Experiment Video
Updated: Aug 2, 2026

07:22
Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
Latex allergy: an update for the otolaryngologist
M L Kashima1, D E Tunkel, C W Cummings
1Johns Hopkins Outpatient Center, Room 6231, 601 N Caroline St, Baltimore, MD 21287-0910, USA.
Archives of Otolaryngology--Head & Neck Surgery
|May 5, 2001
Summary
Latex allergy can cause severe intraoperative reactions in otolaryngology patients, especially those with a history of multiple surgeries. Increased awareness is crucial for identifying and managing this risk.
Area of Science:
- Otolaryngology
- Allergy and Immunology
- Anesthesiology
Background:
- Latex allergy presents a significant risk during surgical procedures.
- Identifying patients at risk and understanding clinical manifestations are critical for patient safety.
Observation:
- This case series describes three patients with severe intraoperative latex allergy reactions.
- Manifestations included cardiorespiratory compromise, rash, bronchospasm, oxygen desaturation, hypotension, and ventilatory difficulties.
Findings:
- All patients had confirmed latex allergy via positive latex-specific IgE tests.
- Risk factors identified include a history of multiple surgical procedures and long-term latex exposure.
Implications:
- Otolaryngologists must maintain a high index of suspicion for latex allergy in patients with unexplained intraoperative events.
- Implementing latex-safe protocols is essential for managing patients with known or suspected latex allergy.
Related Concept Videos
Allergic Reactions
Overview
Asthma-I: Introduction
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-IV: Diagnostic and Management
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma I: Introduction
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma III: Clinical Manifestations
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

