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Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome
Published on: September 13, 2020
Outcome after thrombolysis and selective thoracic outlet decompression for primary axillary vein thrombosis
R Lokanathan1, A J Salvian, J C Chen
1Division of Vascular Surgery, University of British Columbia, Vancouver, Canada.
Insights
Thrombolysis and selective thoracic outlet decompression effectively treat primary subclavian-axillary vein thrombosis (SAVT), leading to good functional outcomes. The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire is valuable for assessing patient recovery.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Patient Outcomes
Background:
- Primary subclavian-axillary vein thrombosis (SAVT) is a serious condition.
- Current treatment involves thrombolysis and anticoagulation, with thoracic outlet decompression reserved for select cases.
Purpose of the Study:
- To review functional outcomes of patients treated for SAVT.
- To evaluate the efficacy of thrombolysis and selective thoracic outlet decompression.
Main Methods:
- Retrospective review of 28 patients treated for SAVT over 10 years.
- Diagnosis confirmed by venography.
- Functional outcomes assessed using the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire.
Main Results:
- 25 patients received thrombolysis; 12 underwent angioplasty for residual stenosis.
- Two patients had decompressive surgery.
- At a mean follow-up of 2.9 years, 28% were symptom-free, 62% had mild symptoms, and 20% reported work difficulties.
Conclusions:
- Thrombolysis with selective thoracic outlet decompression is a viable therapeutic approach for SAVT with acceptable morbidity.
- The DASH questionnaire is a useful tool for evaluating SAVT treatment outcomes.
Purpose:
Treatment for primary subclavian-axillary vein thrombosis (SAVT) at our institution consists of thrombolysis and anticoagulation for 3 months. Thoracic outlet decompression has been performed for a small number of patients. We wanted to review the functional outcomes of patients treated in such a manner.
Material And Methods:
The records of all patients treated for a first episode of SAVT at our hospital over the past 10 years were reviewed. Demographics, comorbidities, method of diagnosis, and treatment for SAVT were recorded. Long-term follow-up was obtained by chart review and asking patients to complete the DASH (disabilities of the arm, shoulder and hand) questionnaire that was developed by the American Academy of Orthopedic Surgeons.
Results:
Twenty-eight patients, 20 men and eight women, with a mean age of 36 were treated during the study period. The median time between onset of symptoms and treatment was 5.5 (range, 1-100) days. All patients had confirmation of the diagnosis by venography. Twenty-five patients received thrombolytic treatment with catheter-directed infusions of urokinase; in the other three patients the vein was chronically occluded. Twelve patients had some degree of residual stenosis and were treated with percutaneous transluminal angioplasty after thrombolysis. During the study period two patients underwent decompressive surgery. Twenty-one patients responded to the DASH questionnaire a mean of 2.9 years (range, 2 months to 8 years) after the episode of SAVT. Six (28%) of 21 patients were completely symptom free, 13 patients (62%) had DASH scores consistent with mild symptoms, and two patients had more severe symptoms. Twenty percent (4 of 21) of patients report some difficulty with work.
Conclusions:
Thrombolysis, followed by selective thoracic outlet decompression on the basis of the severity of patients' symptoms can be used as a therapeutic approach to SAVT without undue morbidity. The DASH questionnaire is a useful tool to evaluate results after therapy for SAVT.
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