Related Experiment Videos
Cardiac malignant lymphoma successfully treated with chemotherapy
N Cordel1, C E. Geffroy, C Capet
1Department of Geriatric Medicine, C.H.U. Rouen Hôpital de Bois-Guillaume, 76031 Cedex, Rouen, France
European Journal of Internal Medicine
|April 12, 2001
Summary
An 83-year-old woman with cardiac diffuse large B-cell lymphoma experienced heart failure. Monochemotherapy with cyclophosphamide led to complete and sustained tumor disappearance, offering a potential treatment for cardiac lymphoma.
Area of Science:
- Cardiology
- Oncology
- Hematology
Background:
- Cardiac tumors are rare, with lymphoma being an uncommon primary or secondary malignancy.
- Diffuse large B-cell lymphoma (DLBCL) can rarely infiltrate the heart, presenting with diverse clinical manifestations.
- Congestive heart failure can be an initial sign of cardiac involvement by lymphoma.
Purpose of the Study:
- To report a rare case of right ventricular diffuse large B-cell lymphoma presenting as acute congestive heart failure.
- To highlight the efficacy of monochemotherapy in managing cardiac lymphoma.
Main Methods:
- Case report of an 83-year-old female patient.
- Diagnosis of diffuse large B-cell lymphoma in the right cardiac ventricle.
- Treatment with cyclophosphamide monochemotherapy.
Main Results:
- The patient presented with acute congestive heart failure.
- Imaging confirmed a large tumor in the right ventricle.
- Following cyclophosphamide treatment, complete and long-lasting disappearance of the cardiac tumor was achieved.
Conclusions:
- Diffuse large B-cell lymphoma of the heart is a rare entity that can mimic primary cardiac diseases.
- Monochemotherapy with cyclophosphamide can be an effective treatment for cardiac lymphoma, leading to durable remission.
- Early diagnosis and prompt treatment are crucial for managing cardiac lymphoma presenting with heart failure.