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Related Experiment Videos

Contact urticaria.

S H Wakelin1

  • 1Department of Dermatology, St Mary's Hospital, London, UK.

Clinical and Experimental Dermatology
|April 12, 2001
PubMed
Summary
This summary is machine-generated.

Contact urticaria, often under-recognized, can be irritant or allergic. Allergic reactions, triggered by substances like latex, involve hypersensitivity and can be severe.

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Area of Science:

  • Dermatology
  • Allergology
  • Immunology

Background:

  • Contact urticaria is a skin reaction to various substances.
  • It can be non-immunological (irritant) or immunological (allergic).
  • Prevalence is unknown but potentially common and under-recognized.

Purpose of the Study:

  • To differentiate between irritant and allergic contact urticaria.
  • To highlight key causes and diagnostic methods for immunological contact urticaria.

Main Methods:

  • Literature review on contact urticaria causes and mechanisms.
  • Discussion of diagnostic approaches including skin prick testing and IgE measurement.

Main Results:

  • Non-immunological reactions are typically mild and localized.

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  • Immunological reactions are immediate-type hypersensitivity, potentially severe, and common in atopic individuals.
  • Natural rubber latex is a significant cause of allergic contact urticaria.

    • Conclusions:

    • Contact urticaria requires careful diagnosis to distinguish irritant from allergic types.
    • Allergic contact urticaria, especially from latex, is a growing concern.
    • Diagnostic tools like skin prick testing aid in confirming immunological reactions.