Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Epstein-Barr virus infectious mononucleosis.

M Papesch¹, R Watkins

¹Department of Otolaryngology/Head and Neck Surgery, Whipps Cross Hospital, Paddington, London, UK.

Clinical Otolaryngology and Allied Sciences

|April 12, 2001

Summary

Epstein-Barr virus (EBV) causes infectious mononucleosis. This review covers EBV

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Review of the Management of Obesity in Primary Care.

Clinical obesity·2025

Same author

"What counts can't always be measured": a qualitative exploration of general practitioners' conceptualisation of quality for community pharmacy services.

BMC family practice·2020

Same author

The experiences of physiotherapists treating people with dementia who fracture their hip.

BMC geriatrics·2017

Same author

Introduction of an outpatient clinic safety checklist: our experience.

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·2016

Same author

Leukaemic infiltration of gall bladder - unusual presentation of occult chronic lymphocytic leukaemia.

Journal of surgical case reports·2014

Same author

Components of genetic variance for plant survival and vigor of apple trees.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2014

Area of Science:

Virology
Immunology
Infectious Diseases

Background:

Epstein-Barr virus (EBV) is the primary cause of infectious mononucleosis.
Understanding EBV's antigenicity and the host's immune response is crucial for diagnosis and management.

Purpose of the Study:

To review the antigenicity of Epstein-Barr virus (EBV).
To discuss antibody responses, diagnostic tests, complications, and management of EBV infections.

Main Methods:

Literature review of EBV antigenicity, antibody responses, and diagnostic methods.
Analysis of diagnostic test performance, including Monospot test limitations.
Compilation of information on EBV-associated complications and treatment strategies.

Main Results:

EBV triggers specific antibody responses and polyclonal heterophile antibodies.
Diagnostic tests vary in accuracy; the Monospot test has known pitfalls.
Splenic rupture is a significant complication, necessitating avoidance of contact sports.

Conclusions:

Accurate diagnosis of EBV infection requires careful consideration of various tests and clinical presentation.
Management focuses on symptomatic relief and preventing serious complications like splenic rupture.
Steroid use in EBV infections requires careful consideration of benefits and risks.

Related Experiment Videos