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Related Experiment Videos

Late-onset hydroa vacciniforme: two case reports.

S N Wong1, S H Tan, S W Khoo

  • 1National Skin Centre, 1 Mandalay Road, Singapore 308205. s_nwong@nsc.gov.sg

The British Journal of Dermatology
|April 12, 2001
PubMed
Summary

Hydroa vacciniforme (HV), a rare blistering skin condition, typically starts in childhood. This study highlights two unusual late-onset cases in adults, one with atypical symptoms, presenting diagnostic challenges.

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Area of Science:

  • Dermatology
  • Photodermatology
  • Rare diseases

Background:

  • Hydroa vacciniforme (HV) is a rare blistering photodermatosis.
  • It typically presents in childhood and resolves by early adulthood.
  • Vacciniform scarring is a characteristic healing pattern.

Observation:

  • Two cases of late-onset HV (at 20 years) were observed.
  • Both cases occurred during compulsory military service.
  • One patient presented with a non-vesicular, atypical form of HV.

Findings:

  • Late onset of Hydroa vacciniforme is possible.
  • Atypical presentations can mimic other dermatological conditions.
  • Diagnostic challenges arise with non-classical HV symptoms.

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Implications:

  • Highlights the importance of considering HV in adult-onset blistering photodermatoses.
  • Suggests environmental or stress factors (e.g., military service) may play a role in late onset.
  • Emphasizes the need for thorough dermatological evaluation for atypical presentations.