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Osler-Weber-Rendu syndrome. Urologist's view
Two patients had hereditary hemorrhagic telangiectasia with hematuria. Characteristic telangiectasia was demonstrated in the bladder, prostate, and prostatic urethra of 1 patient; the other had a bladder tumor. Pathophysiologic aspects and treatment of the syndrome are discussed. Hematuria in patients with hereditary hemorrhagic telangiectasia demands urologic investigation to rule out the common causes of urinary tract bleeding; conversely, this disease should be included among possible diagnoses in patients with hematuria of obscure origin.
Two patients had hereditary hemorrhagic telangiectasia with hematuria. Characteristic telangiectasia was demonstrated in the bladder, prostate, and prostatic urethra of 1 patient; the other had a bladder tumor. Pathophysiologic aspects and treatment of the syndrome are discussed. Hematuria in patients with hereditary hemorrhagic telangiectasia demands urologic investigation to rule out the common causes of urinary tract bleeding; conversely, this disease should be included among possible diagnoses in patients with hematuria of obscure origin.