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Transfusion practice in elective orthopaedic surgery.
B G Feagan1, C J Wong, C Y Lau
1London Clinical Trials Research Group, The John P. Robarts Research Institute, London, Ontario, Canada. feagan@lctrg.com
Autologous blood donation (ABD) significantly reduced allogeneic transfusion rates in hip and knee arthroplasty patients. Encouraging eligible patients to predonate blood is key to lowering transfusion needs.
Area of Science:
- Orthopedic Surgery
- Transfusion Medicine
- Patient Blood Management
Background:
- Total hip and knee arthroplasty procedures have significant transfusion requirements.
- Autologous blood donation (ABD) is a potential strategy to mitigate these needs.
- Current utilization of ABD programs in arthroplasty patients is low.
Purpose of the Study:
- To evaluate transfusion requirements in total hip and knee arthroplasty patients.
- To assess the uptake and effectiveness of autologous blood donation (ABD) programs.
- To identify risk factors for allogeneic transfusions and evaluate predictive models.
Main Methods:
- Retrospective analysis of 2233 patients undergoing hip or knee arthroplasty.
- Comparison of transfusion rates between patients who predonated autologous blood and those who did not.
- Identification of risk factors associated with allogeneic transfusions.
Main Results:
- Only 8% of eligible patients (64% of total) predonated blood.
- Patients who predonated had significantly lower allogeneic transfusion rates (9.0% vs. 24.1%).
- Key risk factors for allogeneic transfusion included procedure type, lower hemoglobin, lower weight, older age, and rheumatoid arthritis.
Conclusions:
- Autologous blood donation (ABD) is effective in reducing allogeneic transfusion rates in arthroplasty patients.
- There is a substantial gap between eligibility for ABD and actual participation.
- Increased promotion of ABD and implementation of alternative strategies for ineligible patients are necessary to reduce allogeneic transfusion rates.
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