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Related Experiment Videos

Transfusion practice in elective orthopaedic surgery.

B G Feagan1, C J Wong, C Y Lau

  • 1London Clinical Trials Research Group, The John P. Robarts Research Institute, London, Ontario, Canada. feagan@lctrg.com

Transfusion Medicine (Oxford, England)
|April 12, 2001
PubMed
Summary
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Autologous blood donation (ABD) significantly reduced allogeneic transfusion rates in hip and knee arthroplasty patients. Encouraging eligible patients to predonate blood is key to lowering transfusion needs.

Area of Science:

  • Orthopedic Surgery
  • Transfusion Medicine
  • Patient Blood Management

Background:

  • Total hip and knee arthroplasty procedures have significant transfusion requirements.
  • Autologous blood donation (ABD) is a potential strategy to mitigate these needs.
  • Current utilization of ABD programs in arthroplasty patients is low.

Purpose of the Study:

  • To evaluate transfusion requirements in total hip and knee arthroplasty patients.
  • To assess the uptake and effectiveness of autologous blood donation (ABD) programs.
  • To identify risk factors for allogeneic transfusions and evaluate predictive models.

Main Methods:

  • Retrospective analysis of 2233 patients undergoing hip or knee arthroplasty.
  • Comparison of transfusion rates between patients who predonated autologous blood and those who did not.

Related Experiment Videos

  • Identification of risk factors associated with allogeneic transfusions.

    • Main Results:

    • Only 8% of eligible patients (64% of total) predonated blood.
    • Patients who predonated had significantly lower allogeneic transfusion rates (9.0% vs. 24.1%).
    • Key risk factors for allogeneic transfusion included procedure type, lower hemoglobin, lower weight, older age, and rheumatoid arthritis.

    Conclusions:

    • Autologous blood donation (ABD) is effective in reducing allogeneic transfusion rates in arthroplasty patients.
    • There is a substantial gap between eligibility for ABD and actual participation.
    • Increased promotion of ABD and implementation of alternative strategies for ineligible patients are necessary to reduce allogeneic transfusion rates.