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Related Experiment Videos

Method for measuring long-term function of muscle-powered implants via radiotelemetry.

D R Trumble1, J A Magovern

  • 1Cardiothoracic Surgery Research, Allegheny-Singer Research Institute, and Department of Surgery, Allegheny General Hospital, West Penn Allegheny Health System, Pittsburgh, Pennsylvania 15212, USA. trumble@wpahs.org

Journal of Applied Physiology (Bethesda, Md. : 1985)
|April 12, 2001
PubMed
Summary

Remote monitoring of muscle-powered implants is now possible with an adjustable workload system. This method avoids invasive lines and animal stress, enabling accurate long-term device function assessment in trials.

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Area of Science:

  • Biomedical Engineering
  • Implantable Devices
  • Remote Monitoring Technologies

Background:

  • Long-term monitoring of muscle-powered implants traditionally requires percutaneous access, leading to complications like infection and animal stress.
  • Untethered, long-term in vivo studies are crucial for evaluating the efficacy and durability of novel implantable devices.

Purpose of the Study:

  • To develop and validate a novel method for the long-term remote monitoring of muscle-powered implantable devices.
  • To assess the accuracy of a remotely adjustable workload system for evaluating device function without percutaneous access.

Main Methods:

  • Development of an adjustable workload system comprising a latex bladder, hermetically sealed canister, multichannel telemetry unit, and subcutaneous access port.
  • In vitro validation using a third-generation muscle energy converter functioning as an implantable hydraulic pump.

Related Experiment Videos

  • Collection of telemetered pressure data to calculate six indexes of device function and comparison with measured values.

    • Main Results:

    • High correlation between measured and calculated device function parameters.
    • Accuracy of the monitoring method demonstrated with most estimates yielding errors of less than 3%.
    • Successful remote adjustment of workload and data acquisition for device assessment.

    Conclusions:

    • The developed adjustable workload system enables effective long-term remote monitoring of muscle-powered implants.
    • This technique eliminates the need for percutaneous lines, reducing animal stress and infection risks.
    • The validated method supports the use of this approach in long-term animal trials for implantable devices.