Congenital CMV with callosal lipoma and agenesis

An infant with symptomatic congenital Cytomegalovirus infection is reported. After the detection of abnormalities on cranial ultrasound scanning, magnetic resonance imaging of the brain revealed a complete absence of corpus callosum with a midline anterior tubulonodular lipoma. A proposed causative link between early in utero Cytomegalovirus infection and lipoma with agenesis of corpus callosum is discussed.