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Notch pathway: making sense of suppressor of hairless
1Department of Anatomy, University of Cambridge, Downing Street, CB2 3DY, Cambridge, UK. sjb32@mole.bio.cam.ac.uk
Current Biology : CB
|April 13, 2001
Abstract:
Suppressor of Hairless (Su(H)) is a DNA-binding protein component of the Notch signalling pathway, thought to be required, with a fragment of the Notch receptor, for target gene activation. Recent studies show that this is only one side of the story: target gene enhancers may be regulated by Su(H) in a variety of different ways.