Crinane and lycorane type alkaloids from Zephyranthes citrina

Area of Science:

• Phytochemistry
• Natural Product Chemistry
• Organic Chemistry

Background:

• Zephyranthes citrina, a member of the Amaryllidaceae family, is a potential source of bioactive compounds.
• Alkaloids are a diverse group of naturally occurring organic compounds that contain basic nitrogen atoms.

Discussion:

• This study details the isolation and characterization of eight alkaloids from Zephyranthes citrina.
• Oxomaritidine is identified for the first time from a natural source, highlighting novel chemical diversity.
• The structural and stereochemical elucidation employed advanced physical and spectroscopic methods.

Key Insights:

• Isolation of eight alkaloids from Zephyranthes citrina.
• First-time natural occurrence report of the alkaloid oxomaritidine.
• Comprehensive structural and stereochemical determination of isolated alkaloids.

Outlook:

• Further investigation into the biological activities of these alkaloids may reveal therapeutic potential.
• This discovery contributes to the chemotaxonomic understanding of the Amaryllidaceae family.
• The findings provide a basis for synthetic studies and the development of new pharmaceutical agents.