Renal biopsy studies in 150 children with non-specific glomerulopathy

The experience with light microscopic examination of kidney biopsies in 150 children with nonspecific glomerulopathy is reported. Most major types of glomerular lesions, as they are at present known, were observed but in a very uneven distribution. Four groups of clinical symptoms were observed in the primary as well as in the associated non-specific glomerulopathies: hematuria, proteinuria, acute nephritic syndrome and nephrotic syndrome. Although in a number of instances, the histologic lesion was suggested by the clinical picture, a correlation was lacking in most instances. More information was obtained from the histology when the evolution was considered, particularly in the primary nephrotic syndrome and the Schönlein-Henoch nephropathy.