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Recurrent Legg-Calvé-Perthes disease: case report and long-term followup
D B Stevens1, S S Tao, C J Glueck
1Shriners Hospital for Children, Lexington, KY 40502-1298, USA.
Clinical Orthopaedics and Related Research
|April 17, 2001
Summary
This case study details recurrent Legg-Calvé-Perthes disease in a young boy, highlighting its initial onset, healing, and subsequent recurrence. Investigations explored hypercoagulability and genetic factors in pediatric osteonecrosis.
Area of Science:
- Pediatric Orthopedics
- Hematology
- Genetics
Background:
- Legg-Calvé-Perthes disease (LCPD) is a childhood hip condition involving avascular necrosis of the femoral head.
- Recurrence of LCPD is rare, with limited documented cases, making this report significant for understanding disease patterns.
Observation:
- The case involves a male patient experiencing LCPD at age 4, with initial clinical and radiographic healing.
- Disease recurrence was observed at age 8, with follow-up extending to age 20.
Findings:
- The study reports on hypercoagulability and hypofibrinolysis blood tests in the patient.
- Genetic factors potentially relevant to bone osteonecrosis were also investigated.
Implications:
- This case contributes to the understanding of recurrent Legg-Calvé-Perthes disease, a condition with few reported instances.
- Further research into hemostatic and genetic factors may elucidate mechanisms behind LCPD recurrence in children.