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Related Experiment Video

Updated: Jun 11, 2026

Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
10:12

Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles

Published on: January 7, 2019

Using selective withdrawal to coat microparticles.

I Cohen1, H Li, J L Hougland

  • 1James Frank Institute and Department of Physics, Department of Chemistry, University of Chicago, Chicago, IL 60637, USA.

Science (New York, N.Y.)
|April 17, 2001
PubMed
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This study introduces a novel fluid dynamics method for polymer coating small particles. The technique enables controllable, conformal polymer film deposition on particles for advanced material applications.

Area of Science:

  • Materials Science
  • Fluid Dynamics
  • Nanotechnology

Background:

  • Developing methods for uniform polymer coating on small particles is crucial for advanced materials.
  • Existing techniques may lack control over coating thickness and chemical composition.

Purpose of the Study:

  • To present a new technique for polymer film coating on small particles using selective fluid withdrawal.
  • To demonstrate control over coating thickness and chemical versatility.

Main Methods:

  • Utilizing a water-oil interface and controlled fluid withdrawal through a tube.
  • Entraining particles and prepolymer reagents in a water spout within an immiscible oil phase.
  • Inducing spout interface break to form polymer coatings, followed by polymerization.

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Related Experiment Videos

Last Updated: Jun 11, 2026

Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
10:12

Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles

Published on: January 7, 2019

Preparation of Nanoparticles for ToF-SIMS and XPS Analysis
06:24

Preparation of Nanoparticles for ToF-SIMS and XPS Analysis

Published on: September 13, 2020

Pattern Generation for Micropattern Traction Microscopy
09:26

Pattern Generation for Micropattern Traction Microscopy

Published on: February 17, 2022

Main Results:

  • Achieved controllable thin polymer film coatings on small particles.
  • Demonstrated flexibility in chemical composition and thickness of the conformal coatings.
  • The method allows for subsequent polymerization using various methods (chemical, light, heat).

Conclusions:

  • The selective fluid withdrawal method offers a versatile approach for polymer coating small particles.
  • This technique provides precise control over coating properties, enabling tailored particle functionalities.
  • The method has potential applications in areas requiring precisely coated micro- and nanoparticles.