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October 2000: a 47 year old man with long-standing progressive tetraparesis
J E Pittella1, C C da Costa, A V Giannetti
1Department of Pathology and Forensic Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Brain Pathology (Zurich, Switzerland)
|April 17, 2001
Summary
A rare case of lymphoplasmacyte-rich meningioma caused progressive spinal cord compression and neurological decline. This study details the atypical presentation and histological findings of this dural tumor.
Area of Science:
- Neuropathology
- Neurosurgery
- Oncology
Background:
- Lymphoplasmacyte-rich meningiomas are rare dural tumors, often presenting insidiously.
- Spinal meningiomas can cause significant neurological deficits due to cord compression.
Observation:
- A 47-year-old man presented with progressive tetraparesis and sphincter issues, evolving to tetraplegia.
- Cervical MRI showed an ill-defined, enhancing lesion compressing the spinal cord from C1 to C6.
- Necropsy revealed multiple whitish dural nodes and diffuse thickening.
Findings:
- Histological examination confirmed multiple en plaque lymphoplasmacyte-rich meningiomas.
- The tumor exhibited atypical macroscopic features and a rare histological variant.
- Radiological and pathological findings were correlated with clinical progression.
Implications:
- This case highlights the importance of considering rare meningioma variants in spinal cord compression diagnoses.
- Understanding atypical presentations is crucial for accurate diagnosis and surgical planning.
- Further research into lymphoplasmacyte-rich meningiomas may improve patient outcomes.