Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Maturation of widely distributed brain function subserves cognitive development.

B Luna1, K R Thulborn, D P Munoz

  • 1Neurobehavioral Studies Program, MR Research Center, Pittsburgh, Pennsylvania, USA.

Neuroimage
|April 17, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Jang YJ, et al. Characterizing the relationship between personality dimensions and psychosis-specific clinical characteristics" [Schizophr Res. 276 (2025) 88-96 10.1016/j.schres.2025.01.002 (Epub ahead of print, PMID: 39864301, Jan 25)].

Schizophrenia research·2025
Same author

MIR137 polygenic risk for schizophrenia and ephrin-regulated pathway: Role in lateral ventricles and corpus callosum volume.

International journal of clinical and health psychology : IJCHP·2024
Same author

Emotional scene processing in biotypes of psychosis.

Psychiatry research·2023
Same author

Dynamic intervention-based biomarkers may reduce heterogeneity and motivate targeted interventions in clinical high risk for psychosis.

Schizophrenia research·2022
Same author

Prior differences in previous trauma exposure primarily drive the observed racial/ethnic differences in posttrauma depression and anxiety following a recent trauma.

Psychological medicine·2022
Same author

Substance use patterns in 9-10 year olds: Baseline findings from the adolescent brain cognitive development (ABCD) study.

Drug and alcohol dependence·2021
Same journal

Investigating the Neural Origins of Ear-EEG: A Correlation Study Using Scalp EEG Source Reconstruction.

NeuroImage·2026
Same journal

Hysteresis effects in visual and auditory perception and the comparison of underlying neural mechanisms - an EEG study.

NeuroImage·2026
Same journal

Short-term audio-tactile training affects cortical auditory speech-envelope tracking for incongruent but not congruent stimuli.

NeuroImage·2026
Same journal

Dissociable Neurocognitive Mechanisms of State and Trait Anxiety in Working Memory: Threat-Induced Alterations in Decision Dynamics and Attenuation of Large-Scale Network Reconfiguration.

NeuroImage·2026
Same journal

Neuro-Ocular Amyloid Characterization in Alzheimer's Disease via Cross-Site PET-MRI and Hierarchical Cross-Attention Driven Multimodal Representation Learning.

NeuroImage·2026
Same journal

Whole-brain network dynamics underlying intolerance of uncertainty.

NeuroImage·2026
See all related articles

Brain maturation continues through adolescence, enhancing voluntary control over impulsive behaviors. Functional MRI reveals gradual development of brain activity supporting this cognitive control into adulthood.

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Cognitive Science

Background:

  • Cognitive control and voluntary suppression of impulsive behaviors develop throughout childhood and adolescence.
  • Functional magnetic resonance imaging (fMRI) allows for the study of brain activity changes during cognitive development.

Purpose of the Study:

  • To investigate the cognitive and brain maturation underlying the ability to voluntarily suppress context-inappropriate behavior.
  • To characterize age-related changes in brain activation patterns associated with response inhibition.

Main Methods:

  • Tested 8-30 year olds using an oculomotor response-suppression task.
  • Utilized functional magnetic resonance imaging (fMRI) to measure brain activity during the task.

Related Experiment Videos

Main Results:

  • Behavioral inhibition abilities matured gradually from childhood to adulthood.
  • fMRI showed progressive increases in brain activation in frontal, parietal, striatal, and thalamic regions with age.
  • Adolescents showed higher prefrontal cortex activation, while adults exhibited greater lateral cerebellum activation compared to younger subjects.

Conclusions:

  • Efficient top-down modulation of reflexive actions may not be fully established until adulthood.
  • Maturation of widely distributed brain regions supports the development of voluntary behavioral control.