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Updated: Aug 9, 2026

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
Published on: October 20, 2019
Hydatidiform mole with coexistent fetus
Eight cases of hydatidiform mole with coexistent fetus are presented with special considerations of diagnosis and management. Although the incidence of this condition was one in 22,000 pregnancies, it is emphasized that the combination of a mole with a fetus should be included in the differential diagnosis of patients who have signs and symptoms of gestational trophoblastic disease in the presence of a fetus. Recommended treatment is immediate termination of the pregnancy. Appropriate follow-up with a sensitive and specific gonadotropin assay is required to differentiate minimal tumor activity rom normal levels of pituitary luteinizing hormone. None of the patients in this series developed maligant trophoblastic neoplasia.
Eight cases of hydatidiform mole with coexistent fetus are presented with special considerations of diagnosis and management. Although the incidence of this condition was one in 22,000 pregnancies, it is emphasized that the combination of a mole with a fetus should be included in the differential diagnosis of patients who have signs and symptoms of gestational trophoblastic disease in the presence of a fetus. Recommended treatment is immediate termination of the pregnancy. Appropriate follow-up with a sensitive and specific gonadotropin assay is required to differentiate minimal tumor activity rom normal levels of pituitary luteinizing hormone. None of the patients in this series developed maligant trophoblastic neoplasia.
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