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Published on: February 12, 2017
Metastatic placental site trophoblastic tumor. Report of a case with complete response to chemotherapy
G Mangili1, E Garavaglia, P De Marzi
1Department of Obstetrics and Gynecology, Ospedale San Raffaele, Via Olgettina 60, 20100 Milan, Italy.
Background:
Placental site trophoblastic tumor (PSTT) is a rare form of gestational trophoblastic neoplasia, commonly insensitive to chemotherapeutic agents.
Case:
We report on long-term remission in a patient with metastatic PSTT after etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine combination chemotherapy. The 27-year-old patient with metastatic lung PSTT was alive, without evidence of disease, > 40 months after treatment.
Conclusion:
Treatment with multiagent chemotherapy can produce long-term remission, even in patients with metastatic PSTT.
