Successful management of polyneuropathy associated with IgM gammopathy of undetermined significance with
M Toepfer1, M Schroeder, W Müller-Felber
1Division of Nephrology, Medizinische Klinik, Ludwig-Maximilians-Universität, München, Germany.
Abstract:
Peripheral polyneuropathies associated with monoclonal IgM gammopathy of undetermined significance often have a progressive course and optimal treatment has not been established. We report on a patient diagnosed with polyneuropathy associated with benign IgM gammopathy, who was successfully treated with antibody-based immunoadsorption only. The neurological symptoms of the patient improved continuously over six months of treatment. Controlled trials should be performed to define this indication for antibody-based immunoadsorption therapy.
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