The antibacterial effects of ornidazole on primary molars with infected pulps

The purpose of this study was to investigate the antibacterial effects of a short-term topical application of ornidazole on anaerobic microorganisms. The antibacterial properties of such materials against organisms at infected primary root canals have not been well documented. Twenty infected primary molars in this study were treated using ornidazole (Biteral, Roche). The bacterial contents of the roots were collected with sterile paper points before the application. Freshly mixed ornidazole and sterile saline were placed into the root canals. After 1 week, the bacterial contents of the root canals were collected again. Microbiological analyses were made. Based on our results, it appears that the antibacterial activity of ornidazole caused significant changes in rates of microorganisms (94.53% reduction).