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An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
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Mapping of genes and transcribed sequences in a gene rich 400-kb region on human chromosome 11p15.1-->p14

G M Caldwell1, R L Eddy, C D Day

  • 1Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

Cytogenetics and Cell Genetics
|April 18, 2001
PubMed

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...