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Living-related liver transplantation

A F Bassas1, S H Wali, M S Chehab

  • 1Department of Surgery, Riyadh Armed Forces Hospital, PO Box 7897, Riyadh 11159, Kingdom of Saudi Arabia. Abassas@nesma.net.sa

Saudi Medical Journal
|April 18, 2001
PubMed

Insights

This study details the first pediatric living-related liver transplant in Saudi Arabia for a child with progressive familial intrahepatic cholestasis. The successful procedure utilized a liver segment from the mother, offering a viable solution for pediatric liver disease.

Area of Science:

  • Hepatology
  • Pediatric Surgery
  • Transplantation Medicine

Background:

  • Progressive familial intrahepatic cholestasis (PFIC) is a severe pediatric liver disease.
  • PFIC can lead to intractable pruritus and failure to thrive, necessitating liver transplantation.
  • Cadaveric organ shortages present a significant challenge for pediatric liver transplantation.

Purpose of the Study:

  • To report the first pediatric living-related liver transplant in Saudi Arabia and the Middle East.
  • To demonstrate the feasibility and success of living-related liver transplantation in pediatric patients with PFIC.
  • To highlight living-related liver transplantation as a solution to cadaveric organ scarcity.

Main Methods:

  • A 2-year-old girl diagnosed with PFIC underwent a liver transplant.
  • A segment of the patient's mother's liver was used for the living-related procedure.
  • Post-transplantation care and follow-up were conducted.

Main Results:

  • The pediatric living-related liver transplant was successfully performed.
  • The patient received a segment of her mother's liver.
  • Two years post-transplantation, the patient is reported to be doing well.

Conclusions:

  • Pediatric living-related liver transplantation is a viable and effective option in Saudi Arabia and the Middle East.
  • This approach addresses the critical shortage of cadaveric organs for children requiring liver transplants.
  • Living-related liver transplantation offers a promising solution for managing pediatric liver diseases like PFIC.

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