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Updated: Aug 3, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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Cytokine receptor dimerization and activation: prospects for small molecule agonists

D L Boger1, J Goldberg

  • 1Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. boger@scripps.edu

Bioorganic & Medicinal Chemistry
|April 20, 2001
PubMed
Summary

Ligand-induced receptor dimerization initiates cell signaling. Structural insights into erythropoietin receptor activation guide the search for small-molecule cytokine mimetics.

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