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The new aspects of aminoacyl-tRNA synthetases
M Szymański1, M Deniziak, J Barciszewski
1Institute of Bioorganic Chemistry of the Polish Academy of Sciences, Poznań.
Acta Biochimica Polonica
|April 20, 2001
Abstract:
Aminoacyl-tRNA synthetases (AARS) are essential proteins found in all living organisms. They form a diverse group of enzymes that ensure the fidelity of transfer of genetic information from the DNA into the protein. AARS catalyse the attachment of amino acids to transfer RNAs and thereby establish the rules of the genetic code by virtue of matching the nucleotide triplet of the anticodon with its cognate amino acid. Here we summarise the effects of recent studies on this interesting family of multifunctional enzymes.