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[Are rat alveolar macrophages capable of phagocytizing pollen grains?]
Abstract:
Plane-tree pollen grains were incubated in vitro with alveolar macrophages from inbred Rats, and the possibility of phagocytosis was investigated. No phagocytosis was observed even after 48 hrs incubation. But alveolar cells were bound to pollen grains generally at the apertures. This binding did not require the Fc receptor on the macrophage membrane.
Insights
Alveolar macrophages did not phagocytose plane-tree pollen in vitro. However, these immune cells did bind to pollen grains, independent of Fc receptors, suggesting a non-phagocytic interaction.
Area of Science:
- Immunology
- Cell Biology
- Respiratory Medicine