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Related Experiment Videos

Foot problems in patients with systemic sclerosis.

H Sari-Kouzel1, C E Hutchinson, A Middleton

  • 1University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, UK.

Rheumatology (Oxford, England)
|April 20, 2001
PubMed
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Systemic sclerosis (SSc) patients frequently experience significant foot problems, including pain, ulceration, and circulation issues, often without full awareness. Comprehensive foot care is crucial for managing this disabling condition in SSc patients.

Area of Science:

  • Rheumatology
  • Podiatry
  • Dermatology

Background:

  • Systemic sclerosis (SSc) is a multisystem autoimmune disease characterized by fibrosis, vascular abnormalities, and immune dysregulation.
  • While hand involvement in SSc is well-documented, the prevalence and nature of foot complications are less understood.
  • Patient awareness of foot problems in SSc may be limited, potentially delaying appropriate management.

Purpose of the Study:

  • To investigate the spectrum of foot problems in patients diagnosed with systemic sclerosis (SSc).
  • To evaluate patient-reported symptoms and objective podiatric findings related to foot health in SSc.
  • To assess patient awareness regarding their foot conditions within the context of SSc.

Main Methods:

  • A cohort of 50 unselected patients with SSc underwent comprehensive podiatric assessment.

Related Experiment Videos

  • Methods included clinical examination, patient questionnaires, plasma glucose, foot X-rays, ankle/brachial index, and Doppler ultrasound of digital pulses.
  • Data were collected on reported symptoms, physical abnormalities, footwear issues, and vascular status.

    • Main Results:

    • High prevalence of temperature-related color changes (86%) and cold-induced pain (82%) was reported.
    • Significant podiatric findings included ulcerations (10%), pre-ulcerative lesions (34%), toenail abnormalities (62%), and callus (80%).
    • Radiographic evidence revealed erosions (6%), calcification (17%), osteopenia (26%), and degenerative changes (60%); vascular assessment showed abnormal digital pulses in 79% of patients.

    Conclusions:

    • Foot problems are highly prevalent and a significant source of disability in patients with systemic sclerosis (SSc).
    • Objective podiatric and vascular abnormalities are common, even in patients with limited self-reported issues.
    • Integrated foot care should be a key component of systemic sclerosis management to mitigate disability and improve patient outcomes.