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Related Experiment Videos

2,5-O-methylene-D-mannitol: two polymorphs and the NaI complex.

Y Xiao1, R J Voll, D R Billodeaux

  • 1Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA.

Acta Crystallographica. Section C, Crystal Structure Communications
|April 21, 2001
PubMed
Summary

Two polymorphs of a C7H14O6 compound exhibit distinct hydrogen-bonding patterns. A sodium iodide complex is isomorphous with its NaCl counterpart, with all components on twofold axes.

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Area of Science:

  • Crystallography
  • Solid-state chemistry
  • Carbohydrate chemistry

Background:

  • Mannitol derivatives are important in various chemical and biological applications.
  • Polymorphism and complex formation are critical for understanding material properties.

Purpose of the Study:

  • To characterize the crystal structures and hydrogen-bonding patterns of two polymorphs of (4R,5R,6R,7R)-4,7-bis(hydroxymethyl)-1,3-dioxepane-5,6-diol.
  • To investigate the structural features of its sodium iodide complex and compare it with the analogous sodium chloride complex.

Main Methods:

  • Single-crystal X-ray diffraction at 100 K was used to determine the crystal structures.
  • Analysis of hydrogen bonding and molecular conformations was performed.

Main Results:

Related Experiment Videos

  • Two polymorphs of C7H14O6 were identified, each with Z'=2, differing in hydrogen-bonding arrangements.
  • The sodium iodide complex, NaI.C7H14O6, is isomorphous with the NaCl complex.
  • In the NaI complex, the mannitol derivative, sodium cation, and iodide anion all reside on crystallographic twofold axes.
  • The dioxepane rings in all investigated molecules adopt a twist-chair conformation.

Conclusions:

  • The study elucidates the structural diversity arising from different hydrogen-bonding networks in polymorphs of a mannitol derivative.
  • The isomorphous nature of the NaI and NaCl complexes highlights similarities in their packing and symmetry.
  • The consistent twist-chair conformation of the dioxepane ring provides insight into the conformational preferences of this carbohydrate derivative.