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Blurred vision, left bundle-branch block and cardiac failure.
B P Paelinck1, H De Raedt, V Conraads
1University Hospital Antwerp, Dept. of Cardiology, Edegem, Belgium. Bernard.Paelinck@uza.uia.ac.be
Acta Cardiologica
|April 21, 2001
Summary
Chronic cibenzoline intoxication caused progressive renal impairment, blurred vision, and cardiac failure in a patient. Treatment with catecholamines and Ringer lactate infusions led to complete recovery of cardiac function and symptoms.
Area of Science:
- Pharmacology
- Cardiology
- Nephrology
Background:
- Cibenzoline is an antiarrhythmic drug with potential for toxicity.
- Chronic intoxication can lead to severe systemic effects.
- Renal impairment is a known complication of drug toxicity.
Observation:
- A patient presented with progressive renal impairment.
- Symptoms included blurred vision and cardiac failure.
- Electrocardiogram showed QRS broadening, indicative of cardiac issues.
Findings:
- The patient's condition was diagnosed as chronic cibenzoline intoxication.
- Treatment involved catecholamines to support cardiac function.
- Repetitive infusions of Ringer lactate were administered.
Implications:
- This case highlights the severe manifestations of chronic cibenzoline intoxication.
- Prompt and appropriate medical intervention is crucial for managing drug toxicity.
- Complete recovery is achievable with timely and effective treatment strategies.