Related Experiment Video
Updated: Aug 4, 2026

Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
Some aspects of biochemistry of myocardial infarction
1Department of Experimental Cardiology, Huntington Medical Research Institutes, Pasadena, California 91101, USA. cardio@hmri.org
Abstract:
This review deals with biochemical changes in infarcted heart muscle. Two main topics are emphasized: changes in substrate metabolism and in myocardial nitric oxide (NO), and prostacyclin and thromboxane formation. Alterations in glucose metabolism in infarcted heart are discussed with special reference to its myocardial utilization in ischemia. The biochemical basis of the increase in NO and prostanoids and the relationship between the enzyme producing nitric oxide (NOS) and cyclooxygenases (COX) responsible for formation of prostanoids are described. The relevance of these findings to clinical conditions and to angiogenesis in heart muscle are stressed.
Related Concept Videos
Pathophysiology of Cardiac Performance
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Myocarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome III: Diagnostic Studies

