Tetrachlorodecaoxide does not jeopardize anastomotic healing: an experimental study in animals
Related Experiment Video
Updated: Oct 8, 2026

07:22
Creation of Colonic Anastomosis in Mice
Published on: January 17, 2019
F Schier1, M Bondartschuk, E Danzer
1Department of Pediatric Surgery, University Medical Center Jena, Bachstrasse 18, 07740 Jena, Germany.
Pediatric Surgery International
|April 24, 2001
Abstract:
Tetrachlorodecaoxide (TCDO) is a negatively-charged complex of chlorine and oxygen commonly used for the treatment of infected external wounds. However, it displays antiadhesive properties when applied intra-abdominally. In rats, small-bowel and a large-bowel anastomoses were performed and one-half of the animals received TCDO. It was found that TCDO did not alter the bursting pressures of small and large-bowel anastomoses at 1, 3 and 9 days postoperatively.

