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Related Experiment Video

Updated: Dec 31, 2025

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy

Published on: November 29, 2024

Granulomatous hypophysitis and bilateral optic neuropathy.

E M Arsava¹, K Uluç, T Kansu

¹Department of Neurology, Hacettepe University Hospitals, Ankara, Turkey.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society

|April 24, 2001

Summary

This summary is machine-generated.

Idiopathic granulomatous hypophysitis, a rare pituitary condition, can cause vision loss. This case report details a patient who developed optic neuritis alongside hypophysitis and improved with steroid therapy.

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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

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Published on: December 17, 2010

Area of Science:

Endocrinology
Neuro-ophthalmology

Background:

Idiopathic granulomatous hypophysitis (IGH) is a rare inflammatory condition affecting the pituitary gland.
It can present with diverse symptoms due to pituitary dysfunction and mass effect.

Observation:

A 53-year-old woman presented with hypopituitarism and ophthalmoplegia.
She was diagnosed with IGH and subsequently developed bilateral optic neuritis.

Findings:

The patient demonstrated a positive response to steroid treatment for both hypophysitis and optic neuritis.
This represents the first reported case of granulomatous hypophysitis associated with optic neuritis.

Implications:

This case expands the known clinical spectrum of granulomatous hypophysitis.
It highlights the potential for steroid therapy in managing associated neuro-ophthalmic complications.