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Updated: Jul 29, 2026

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Optimized Fibrin Gel Bead Assay for the Study of Angiogenesis
Published on: April 29, 2007
Basic fibroblast growth factor induced angiogenesis and prefabricated flap survival
1Division of Plastic Surgery, University of Nevada School of Medicine, Las Vegas 89102-2227, USA.
Journal of Reconstructive Microsurgery
|April 24, 2001
Abstract:
Prefabrication of a latissimus dorsi myocutaneous flap was performed in adult male Landrace pigs. Gelfoam sponges were used as a delivery system for basic fibroblast growth factor (bFGF) at the muscle-subcutaneous tissue interface. Skin survival and angiogenesis were augmented in the growth-factor-treated animals. These data support the use of basic fibroblast growth factor to enhance flap prefabrication.
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