Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiac output changes during hyperbaric hyperoxia.

B Neubauer1, K Tetzlaff, C M Staschen

  • 1Health and Safety Department, Employment, Health and Social Welfare Authority, Amt fuer Arbeitsschutz, G2/AS 35, Adolph-Schoenfelder-Strasse 5, 22083 Hamburg, Germany. birger.neubauer@bags.hamburg.de

International Archives of Occupational and Environmental Health
|April 25, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical and genetic spectrum of SCN2A-associated episodic ataxia.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2019
Same author

[Treatment of carbon monoxide poisoning in Germany : A retrospective single center analysis].

Der Anaesthesist·2019
Same author

Last Word on Viewpoint: Why predominantly neurological decompression sickness in breath-hold divers?

Journal of applied physiology (Bethesda, Md. : 1985)·2016
Same author

Why predominantly neurological decompression sickness in breath-hold divers?

Journal of applied physiology (Bethesda, Md. : 1985)·2016
Same author

Antioxidants may Attenuate Plasma Erythropoietin Decline after Hyperbaric Oxygen Diving.

International journal of sports medicine·2015
Same author

[Emergency checklist drowning].

MMW Fortschritte der Medizin·2014
Same journal

Occupational related heat stress exposure and heat-related symptoms among sugarcane workers in Thailand.

International archives of occupational and environmental health·2026
Same journal

Association of volatile organic compounds with serum lactate dehydrogenase levels in the general adults.

International archives of occupational and environmental health·2026
Same journal

Long-term hearing threshold shifts from moderate noise exposure (< 85 dBA time-weighted average) in semiconductor silicon-wafer manufacturing process.

International archives of occupational and environmental health·2026
Same journal

Precarious employment and its associations with perceived stress and self-rated health: a Danish cross-sectional study.

International archives of occupational and environmental health·2026
Same journal

Occupational radiation exposure and cause-specific mortality in a cohort of Canadian medical workers.

International archives of occupational and environmental health·2026
Same journal

Effects of DCBA exposure on liver fibrosis and NAFLD: a comprehensive investigation integrating NHANES data analysis, network toxicology, and molecular docking.

International archives of occupational and environmental health·2026
See all related articles

Increased ambient pressure and oxygen partial pressure significantly decrease cardiac output (Q), heart rate (HR), and stroke volume in divers. This study investigated cardiovascular regulation during simulated diving conditions.

Area of Science:

  • Cardiovascular Physiology
  • Hyperbaric Medicine
  • Exercise Physiology

Background:

  • Cardiovascular regulation is affected by elevated ambient and oxygen partial pressures (pO2) during diving and caisson work.
  • Understanding these effects is crucial for diver safety and performance.

Purpose of the Study:

  • To measure cardiac output (Q) in subjects performing moderate work at a simulated diving depth of 30 meters.
  • To assess the influence of increased ambient pressure and pO2 on cardiovascular parameters.

Main Methods:

  • 23 healthy male Navy divers performed 100 W bicycle exercises in a hyperbaric chamber.
  • Cardiac output (Q) was measured using a CO2-rebreathing technique at 100 kPa and 400 kPa ambient pressures.
  • Subjects were exposed to varying pO2 levels during normobaric and hyperbaric conditions.

Related Experiment Videos

Main Results:

  • A significant decrease in cardiac output (Q), heart rate (HR), and stroke volume was observed at increased ambient pressure.
  • Cardiac output decreased by 64% (8.9 l/min vs. 13.9 l/min) at depth.
  • Mean HR decreased from 104.7 to 94.0 min-1, and stroke volume from 133 ml to 96 ml.

Conclusions:

  • Hyperoxic hyperbaria increases peripheral vascular tonus due to elevated arterial oxygen content.
  • Cardiac output appears to correlate with peripheral vasoconstriction, indirectly influenced by inspiratory pO2 elevation.