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Published on: January 23, 2017
Correlations between risk factors for hearing impairment and TEOAE screening test outcome in neonates at risk for
J Ratyńska1, A Grzanka, M Mueller-Malesińska
1Institute of Physiology and Pathology of Hearing, Warsaw, Poland. ratynska@ifps.org.pl
Insights
Specific risk factors correlate with neonatal hearing impairment. Genetic factors, TORCH infections, and ototoxic drugs lowered TEOAE screening results, while hyperbilirubinemia showed higher SNR values in at-risk newborns.
Area of Science:
- Neonatal audiology
- Pediatric audiology
- Otoacoustic emissions testing
Background:
- Neonatal hearing impairment is a significant concern.
- Early identification of hearing loss is crucial for developmental outcomes.
- Risk factors for neonatal hearing impairment require further investigation.
Purpose of the Study:
- To determine correlations between neonatal hearing impairment risk factors.
- To examine the relationship between these risk factors and TEOAE screening results.
- To identify specific risk factors impacting TEOAE signal-to-noise ratios in at-risk neonates.
Main Methods:
- Study included seventy-one newborns identified as at risk for hearing impairment.
- Analyzed correlations between various specific risk factors.
- Investigated the relationship between risk factors and TEOAE (Transient-Evoked Otoacoustic Emissions) signal-to-noise ratio (SNR).
Main Results:
- Strong correlations were observed between specific risk factors for hearing impairment.
- Neonates with genetic risk factors, TORCH infections, or treated with ototoxic drugs showed significantly lower TEOAE SNRs.
- Hyperbilirubinemic neonates exhibited significantly higher TEOAE SNRs compared to controls.
Conclusions:
- Specific neonatal risk factors significantly influence TEOAE screening outcomes.
- Genetic factors, TORCH infections, and ototoxic drug exposure are associated with poorer TEOAE results.
- Hyperbilirubinemia may have a different predictive value for hearing impairment in neonates.
Abstract:
The aim of the study was to find the correlation between specific risk factors for hearing impairment as well as between risk factors and TEOAE screening results in neonates at risk for hearing impairment. Seventy-one newborns at risk for hearing impairment have been included in the study. Strong correlations between specific risk factors were found. Investigation of the relationship between specific risk factors and TEOAE signal-to-noise ratio (SNR) showed that in children with genetic risk factors, TORCH (toxoplasmosis, rubella, CMV, herpes virus, others) infections and in those treated with ototoxic drugs, the values of SNRs were significantly lower than in children at risk who did not present those factors. In case of hyperbilirubinaemic children the values of SNR were significantly higher than in the controls. In our opinion these relationships may be partially explained by the positive predictive values of these risk factors, but other intrinsic factors may also be involved.
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