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Collagenous colitis in symptomatic subjects without endoscopic morphologic evidence: case report
A Sumberaz1, M Valentini, E Delehaye
1Department of Gastroenterology, San Martino Hospital, Genoa, Italy. alexsumberaz@smartino.ge.it
Panminerva Medica
|April 25, 2001
Summary
Collagenous colitis (CC) is a rare condition. Diagnosis requires colonoscopy with biopsies, even if the colon appears normal during examination, to confirm the disease.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Collagenous colitis (CC) is a rare gastrointestinal disorder with an undefined etiology and pathology.
- Despite various hypotheses, the exact cause and mechanisms of CC remain unclear.
Observation:
- A case report details a female patient with chronic watery diarrhea and a positive fecal occult blood test.
- Endoscopic investigation revealed a morphologically normal colonic mucosa.
Findings:
- Histological examination of biopsy samples confirmed collagenous colitis.
- This case highlights that CC can present with normal-appearing colonic mucosa during endoscopy.
Implications:
- Clinical suspicion should prompt colonoscopy with biopsies, even with a normal endoscopic appearance.
- Accurate diagnosis relies on collaboration between clinicians and pathologists, especially for suspected CC cases.