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Updated: Jul 29, 2026

Microfluidic Chips for In Situ Crystal X-ray Diffraction and In Situ Dynamic Light Scattering for Serial Crystallography
Published on: April 24, 2018
On the routine use of soft X-rays in macromolecular crystallography
M S Weiss1, T Sicker, K Djinovic-Carugo
1Institute of Molecular Biotechnology, Department of Structural Biology and Crystallography, PO Box 100813, D-07708 Jena, Germany. msweiss@imb-jena.de
Abstract:
A diffraction data set has been collected from a blood coagulation factor XIII-Ca(2+) complex crystal at the X-ray diffraction beamline of the ELETTRA synchrotron (Trieste, Italy) at a wavelength of 2.6 A. The data collection could be carried out using the beamline as is, without making any time-consuming changes to the apparatus. Various data-processing schemes have been employed and it has been observed that local or detector scaling procedures are essential for producing the 'best' anomalous differences.
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