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Updated: Aug 6, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
[The premature infant as an anesthesiology problem--case report]
M Tatić1, M Cvejanov-Janca, A Komarcević
1Klinika za decju hirurgiju, Institut za zdravstvenu zastitu dece i omladine, Novi Sad.
Introduction:
In pediatric anesthesia, neonatal anesthesia takes a special place because of its specific problems connected to physiological properties of newborns and their adaptation after birth. Adaptation itself, represents a line of changes in organ function and organ systems for new circumstances of life.
Discussion:
Preoperative evaluation means identification of any present disease that might need preoperative treatment or specific course of anesthesia and surgery, in order to determine the most proper anesthesia regimen for the child. The primary aim of anesthesia is analgesia, unconsciousness and muscle relaxation, keeping vital parameters in optimal state.
Conclusion:
Newborns and infants, as specific age groups, demand special preoperative evaluation and approach to surgery. Knowledge of newborn's physiology and pathology either congenital or acquired is necessary for optimal choice of anesthesia regimen and surgical procedure in order to minimise postoperative complications.

