Cigarette smoking, blood pressure and serum lipids and lipoproteins in middle-aged women

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Published on: September 27, 2024

H Imamura1, N Miyamoto, K Uchida

  • 1Laboratory of Nutrition and Exercise Physiology, Department of Food and Nutrition, Nakamura Gakuen University. imamura@cc.nakamura-u.ac.jp

Journal of Physiological Anthropology and Applied Human Science
|April 26, 2001
PubMed

Insights

Cigarette smoking is linked to changes in blood pressure and cholesterol levels in middle-aged women. While not dose-dependent, smoking negatively impacts systolic blood pressure (SBP) and diastolic blood pressure (DBP), and favorably affects HDL-C.

Area of Science:

  • Cardiovascular Health
  • Lipid Metabolism
  • Public Health

Background:

  • Cigarette smoking is a major public health concern with known cardiovascular risks.
  • Understanding its specific impact on blood pressure and serum lipids in middle-aged women is crucial for targeted interventions.

Purpose of the Study:

  • To investigate the association between cigarette smoking and blood pressure (systolic and diastolic).
  • To examine the relationship between cigarette smoking and serum lipids and lipoproteins, including HDL-C, TC/HDL-C, TG, and LDL-C.

Main Methods:

  • Cross-sectional study of 3934 middle-aged women (40-59 years).
  • Statistical analyses including adjustment for age, BMI, alcohol intake, and physical activity.
  • Forward stepwise multiple regression was used to identify relationships.

Main Results:

  • Significant mean differences in SBP, DBP, HDL-C, TC/HDL-C, and TG were observed between smokers and non-smokers.
  • Multiple regression revealed negative associations between smoking and SBP, DBP, and HDL-C.
  • Positive associations were found between smoking and TC/HDL-C, TG, Log TG, and LDL-C.

Conclusions:

  • Cigarette smoking is negatively associated with systolic and diastolic blood pressure in middle-aged women.
  • Smoking shows unfavorable associations with key serum lipid and lipoprotein profiles, including HDL-C, TG, and LDL-C.
  • These findings underscore the detrimental cardiovascular effects of smoking in this demographic.

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