Tongue-base hamartoma in tuberous sclerosis
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Updated: Oct 8, 2026
Fabrication of Tongue Extracellular Matrix and Reconstitution of Tongue Squamous Cell Carcinoma In Vitro
Published on: June 20, 2018
H Wallace1, A Davis, A Spedding
1Department of Otolaryngology, Queen Alexandra Hospital, Portsmouth, UK.
Abstract:
This paper describes the case of a 41-year-old female with tuberous sclerosis who presented with a large tongue-base hamartoma. The surgical management of the patient was complicated by the presence of a large thyroid goitre. Awake fibre-optic intubation, thyroidectomy then tracheostomy were necessary before the tongue-base hamartoma could be safely resected. To the best of our knowledge, this is the first reported case of a tongue-base hamartoma in a patient with tuberous sclerosis.
